LOXONIN PRO Physical

Newly Released
Release date: Tuesday, September 9, 2025

Class 1 Drug

A prescription designed to address the causes of severe lower back pain, stiff shoulders, and joint pain

Antipyretic Analgesic
Tablet
15 years of age and older

Attached document
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Product Q&A

Photo: LOXONIN PRO Physical packaging and product

Photo: Dosage form and shape of LOXONIN PRO Physical

This is an explanation of the "Dosage and Administration" and "Precautions for Use" for LOXONIN PRO Physical. Please refer to the "Dosage and Administration" and "Precautions for Use" on this page.

Manufacturer's suggested retail price *Tax included

12錠　823円 / 24錠　1,408円

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"LOXONIN PRO Physical" is an antipyretic and analgesic that works quickly from the inside to relieve pain in the lower back, shoulders, and other parts of the body.

●Contains a pain-relieving ingredient (lofecoxib sodium hydrate) that quickly relieves pain.

●Contains two ingredients (dried peony extract and dried licorice extract) that address the mechanism of pain in the lower back, shoulders, and other parts of the body. It relieves pain caused by muscle tension and inflammation.

●Contains ingredients (magnesium oxide) that are gentle on the stomach.

●Does not contain any ingredients that cause drowsiness (sedative hypnotic ingredients).

●It is a small tablet that is easy to swallow.
Things to avoid
(If these guidelines are not followed, your current symptoms may worsen and side effects are more likely to occur.)
This medicine should not be taken by the following people.

Those who have experienced allergic symptoms due to this drug or its ingredients

Those who have experienced asthma after taking this drug or other antipyretics, analgesics, or cold medicines

Children under 15 years of age

Those receiving the following treatment at a medical institution
Gastric and duodenal ulcers, liver disease, kidney disease, heart disease

Those who have been diagnosed by a doctor with a blood abnormality (blood disease) such as low red blood cell count (anemia), low platelet count (difficulty in clotting or bleeding easily), or low white blood cell count

Pregnant women who are due within 12 weeks of delivery

Do not take any of the following medicines while taking this drug:
Other antipyretics, analgesics, cold medicines, and sedatives

Do not drink alcohol before or after taking this medicine.

Do not take continuously for long periods of time.

(If symptoms such as pain persist after taking the medicine for 3 to 5 days, discontinue use and consult a doctor.)
Things to consult
The following people should consult a doctor, dentist or pharmacist before taking this medicine.

People receiving treatment from a doctor or dentist

Pregnant women or those thought to be pregnant

Breastfeeding

senior citizen

People who have had allergic reactions to medicines, etc.

People who have been diagnosed with
Bronchial asthma, ulcerative colitis, Crohn's disease, systemic lupus erythematosus, mixed connective tissue disease

People who have had the following diseases:
Gastric and duodenal ulcers, liver disease, kidney disease, blood disease

If you experience any of the following symptoms after taking this medicine, these may be side effects, so stop taking the medicine immediately and consult a doctor, dentist, or pharmacist with this leaflet.

If symptoms such as excessive drop in body temperature, weakness, or cold extremities (cold hands and feet) appear after taking an antipyretic analgesic such as this drug.

If you experience peptic ulcer or swelling after taking the medicine
In rare cases, serious symptoms such as gastrointestinal bleeding (vomiting blood, nausea, vomiting, abdominal pain, black tarry stools, bloody stools, etc.) may occur, gastrointestinal perforation (a hole in the gastrointestinal tract, causing nausea, vomiting, severe abdominal pain, etc.), and small or large intestinal stenosis or obstruction (causing nausea, vomiting, abdominal pain, abdominal distension, etc.). If this occurs, consult a doctor immediately.

If the following symptoms occur after taking this medicine:

Affected area: Symptoms

Skin: rash, redness, itching

Digestive system: abdominal pain, stomach discomfort, loss of appetite, nausea/vomiting, abdominal distension, heartburn, stomatitis, indigestion

Circulatory system: Increased blood pressure, palpitations

Neuropsychiatric: drowsiness, numbness, dizziness, headache

Other: Chest pain, fatigue, facial flushing, fever, anemia, hematuria

In rare cases, the following serious symptoms may occur. If this occurs, consult a doctor immediately.

Name of symptom: Symptom

Shock (anaphylaxis): Immediately after taking the medicine, symptoms may include itchy skin, hives, hoarseness, sneezing, itchy throat, shortness of breath, palpitations, and confusion.

Blood disorders: Symptoms include sore throat, fever, general fatigue, paleness of the face or the back of the eyelids, increased bleeding (bleeding gums, nosebleeds, etc.), and blue bruises (which do not go away when pressed).

Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, acute generalized exanthematous pustulosis: High fever, bloodshot eyes, eye discharge, sores on the lips, sore throat, widespread rash/redness on the skin, blisters appearing on the red areas of the skin, small bumps (pustules) appearing on the red skin, general fatigue, loss of appetite, etc. may persist or suddenly worsen.

Kidney damage: Symptoms include fever, rash, decreased urine output, generalized swelling, general fatigue, joint pain (pain in the joints), and diarrhea.

Congestive heart failure: Symptoms include general fatigue, palpitations, shortness of breath, chest discomfort, chest pain, dizziness, and fainting.

Myocardial infarction: squeezing chest pain, shortness of breath, cold sweat.

Cerebrovascular disorder: Symptoms such as sudden decrease or loss of consciousness, difficulty moving one side of the limbs, headache, vomiting, dizziness, difficulty speaking, and difficulty speaking may suddenly appear.

Interstitial pneumonia: When climbing stairs or exerting yourself slightly, you may experience shortness of breath, difficulty breathing, dry cough, fever, etc. These symptoms may appear suddenly or persist.

Liver dysfunction: Symptoms include fever, itching, rash, jaundice (yellowing of the skin or whites of the eyes), brown urine, general fatigue, and loss of appetite.

Rhabdomyolysis: Symptoms include muscle pain in the arms, legs, shoulders, waist, etc., numbness, weakness, stiffness in the arms and legs, general fatigue, and reddish-brown urine.

Aseptic meningitis: Symptoms include severe headache accompanied by stiffness in the neck, fever, nausea, vomiting, etc.

(Such symptoms are particularly common in people being treated for systemic lupus erythematosus or mixed connective tissue disease.)

Asthma: Symptoms include wheezing, whistling, and shortness of breath when breathing.

The following symptoms may occur after taking this medicine. If these symptoms persist or worsen, stop taking this medicine and consult your doctor or pharmacist with this leaflet.
Dry mouth, constipation, diarrhea

If symptoms do not improve after taking the medicine 1 or 2 times (this may be due to the possibility of other diseases), stop taking the medicine and consult a doctor, dentist or pharmacist with this leaflet.
* Pain relief for lower back pain, stiff shoulders, joint pain, neuralgia, muscle pain, bruises, fractures, sprains, trauma, headaches, menstrual pain (period pain), toothache, pain after tooth extraction, sore throat, and earache

〇 Reducing fever during chills and fever

Please take the following amount with water or lukewarm water.

Adults (15 years of age and older)
Dosage	2 tablets
Number of doses per day	Up to 2 times. When symptoms appear, avoid taking this medicine on an empty stomach as much as possible. However, if symptoms appear again, you can take a third dose. Please allow at least 4 hours between doses.

Under 15
Dosage	-
Number of doses per day	Please do not take.

(1) Please strictly follow the usage and dosage instructions.
(2) How to take out the tablets

Press firmly with your fingertips on the raised part of the PTP sheet containing the tablets to break the aluminum foil on the back, remove the tablets and take them. (If swallowed by mistake, it may lead to unexpected accidents such as the tablets piercing the esophageal mucosa.)
*Please use this medicine after receiving an explanation from a pharmacist and carefully reading the “Precautions for Use”. If you have allergies, please be sure to consult with us.

This product is a light red film-coated tablet containing the following ingredients in 2 tablets.

Loxoprofen sodium hydrate
Amount 68.1mg (60mg as anhydrous)
Function Suppresses prostaglandin, the source of inflammation and pain.

peony dry extract
Amount 36mg (252mg as crude drug)
Function It helps relieve muscle tension and relieve pain.

Dried extract of Glycyrrhiza
Amount 50.4mg (252mg as raw drug)
Function It helps relieve pain by relieving muscle tension and reducing inflammation.

magnesium oxide
Amount 33.3mg
Function It has the ability to neutralize stomach acid.
[Additives]
Lactose, partially pregelatinized starch, anhydrous silicic acid, croscarmellose sodium, carmellose calcium, calcium stearate, hypromellose, titanium dioxide, macrogol, iron sesquioxide, carnauba
(1) Store in a cool, dry place away from direct sunlight.

(2) Keep out of reach of children.

(3) Do not transfer to other containers. (This may cause misuse or change the quality.)

(4) Do not use products after the expiration date indicated.

Loxoprofen sodium hydrate
Amount	68.1mg (60mg as anhydrous)
Function	Suppresses prostaglandin, the source of inflammation and pain.

peony dry extract
Amount	36mg (252mg as crude drug)
Function	It helps relieve muscle tension and relieve pain.

Dried extract of Glycyrrhiza
Amount	50.4mg (252mg as raw drug)
Function	It helps relieve pain by relieving muscle tension and reducing inflammation.

magnesium oxide
Amount	33.3mg
Function	It has the ability to neutralize stomach acid.

LOXONIN PRO Physical

Packaging unit	12 tablets	24 tablets
Manufacturer's suggested retail price (10% tax included)	748円(823円)	1,280円(1,408円)
JAN Code	4987 107 674548	4987 107 674838
Individual packaging size Width x Depth x Height (mm)	115x20x55	115x25x55