LOXONIN General Cold Medicine

  • Drugs requiring guidance
  • Self-medication tax deductible
For severe colds that you want to deal with quickly
  • General cold remedy
  • Tablet
  • 15 years of age and older
Photo: Package and product of LOXONIN comprehensive cold medicine

Manufacturer's suggested retail price *Tax included

12錠　1,518円 / 24錠　2,178円

Brand site/SNS

Ideal for:

    For those who want to deal with severe cold symptoms early

More Information

  • 1. The antipyretic and analgesic ingredient "loxoprofen sodium hydrate" quickly suppresses the substances (prostaglandins) that cause sore throat and fever, exhibiting analgesic and antipyretic effects.
    2. "Loxoprofen sodium hydrate" is a prodrug formulation that is gentle on the stomach.
    3. Dihydrocodeine phosphate and dl-methylephedrine hydrochloride relieve troublesome coughs, while bromhexine hydrochloride helps to expel phlegm that causes coughing.
    4. The long-acting antihistamine ingredient clemastine fumarate is effective against runny nose and nasal congestion.
    5. Convenient PTP packaging for easy carrying.

    *A prodrug is a type of formulation in which the active ingredient is absorbed into the body and then converted into an active form to exert its effects.

  • Things to avoid

    (If you do not follow these guidelines, your current symptoms may worsen or side effects/accidents may occur more easily.)

    1. Do not take this medicine if you fall into any of the following categories:
    (1) People who have experienced allergic symptoms due to this drug or its ingredients
    (2) People who have experienced asthma after taking this medicine or other cold medicines or antipyretic analgesics.
    (3) Children under 15 years of age
    (4) People receiving treatment at a medical institution for the following conditions: gastric or duodenal ulcers, liver disease, kidney disease, heart disease
    (5) People who have been diagnosed by a doctor with a blood abnormality (blood disease) such as a low red blood cell count (anemia), a low platelet count (difficulty stopping bleeding, easy bleeding), or a low white blood cell count.
    (6) Pregnant women within 12 weeks of their expected delivery date

    2. Do not use any of the following medications while taking this medicine.
    Other cold medicines, antipyretic analgesics, sedatives, cough and expectorant medicines, oral medications containing antihistamines, etc. (oral medications for rhinitis, motion sickness medications, allergy medications, etc.)
    3. Do not drive or operate machinery after taking this medication. (Drowsiness may occur.)
    4. If you are breastfeeding, do not take this medication, or if you do take it, avoid breastfeeding.
    5. Do not drink alcohol before or after taking this medication.
    6. Do not take this medication for more than 5 days.
    7. Do not take an overdose.


    Things to consult


    1. The following people should consult a doctor or pharmacist before taking this medicine.
    (1) People receiving medical treatment from a doctor or dentist
    (2) Pregnant women or those suspected to be pregnant
    (3) Elderly people
    (4) People who have experienced allergic symptoms due to medicine, etc.
    (5) People with the following symptoms:
    High fever, difficulty urinating
    (6) People who have been diagnosed with the following:
    Thyroid dysfunction, diabetes, heart disease, high blood pressure, glaucoma, bronchial asthma, ulcerative colitis, Crohn's disease, systemic lupus erythematosus, mixed connective tissue disease, respiratory dysfunction, obstructive sleep apnea syndrome, obesity
    (7) People who have had the following diseases:
    Gastric and duodenal ulcers, liver disease, kidney disease, blood disease

    2. If the following symptoms are observed after taking this medicine, these may be side effects, so stop taking the medicine immediately and consult a doctor or pharmacist with this leaflet.
    (1) If symptoms such as excessive drop in body temperature, collapse (loss of strength), or cold limbs (cold hands and feet) appear after taking the medicine.
    (2) If you experience peptic ulcers or swelling after taking the medicine.
    In rare cases, serious symptoms such as gastrointestinal bleeding (vomiting blood, nausea, vomiting, abdominal pain, black tarry stools, bloody stools, etc.) may occur, gastrointestinal perforation (a hole in the gastrointestinal tract, causing nausea, vomiting, severe abdominal pain, etc.), and small or large intestinal stenosis or obstruction (causing nausea, vomiting, abdominal pain, abdominal distension, etc.). If this occurs, consult a doctor immediately.
    (3) If the following symptoms occur after taking the medicine:
    Affected area: Symptoms
    Skin: rash, redness, itching
    Digestive system: abdominal pain, stomach discomfort, loss of appetite, nausea, vomiting, abdominal distension, heartburn, stomatitis, indigestion
    Circulatory system: Increased blood pressure, palpitations
    Neuropsychiatric system: numbness, dizziness, headache, excitement, convulsions
    Urinary system: Difficulty urinating, hematuria
    Others: Chest pain, fatigue, facial flushing, fever, anemia

    In rare cases, the following serious symptoms may occur. If this occurs, consult a doctor immediately.
    Symptom name: Symptoms
    Shock (anaphylaxis): Immediately after taking the drug, symptoms may include itchy skin, hives, hoarseness, sneezing, itchy throat, shortness of breath, palpitations, and confusion.
    Blood disorders: Symptoms include sore throat, fever, general fatigue, paleness of the face or the insides of the eyelids, increased bleeding (bleeding gums, nosebleeds, etc.), and blue bruises (which do not go away when pressed).
    Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, acute generalized exanthematous pustulosis: high fever, bloodshot eyes, eye discharge, sores on the lips, sore throat, widespread rash/redness on the skin, blisters appearing on red areas of the skin, small bumps (pustules) appearing on the red skin, generalized fatigue, loss of appetite, etc. may persist or suddenly worsen.
    Kidney damage: Symptoms include fever, rash, decreased urine output, generalized swelling, general fatigue, joint pain, and diarrhea.
    Congestive heart failure: Symptoms include general fatigue, palpitations, shortness of breath, chest discomfort, chest pain, dizziness, and fainting.
    Myocardial infarction...constraining chest pain, shortness of breath, cold sweat.
    Cerebrovascular disorder: Symptoms such as sudden decrease or loss of consciousness, difficulty moving one side of the limbs, headache, vomiting, dizziness, difficulty speaking, and difficulty speaking may occur.
    Interstitial pneumonia: When climbing stairs or exerting yourself slightly, you may experience shortness of breath, difficulty breathing, dry cough, fever, etc. These symptoms may appear suddenly or persist.
    Liver dysfunction: Symptoms include fever, itching, rash, jaundice (yellowing of the skin and whites of the eyes), brown urine, general fatigue, and loss of appetite.
    Rhabdomyolysis: Symptoms include muscle pain in the arms, legs, shoulders, waist, etc., numbness, weakness, stiffness in the arms and legs, general fatigue, and reddish-brown urine.
    Aseptic meningitis: Symptoms include a severe headache accompanied by stiffness in the neck, fever, nausea, vomiting, etc. (These symptoms have been reported frequently, particularly in people receiving treatment for systemic lupus erythematosus or mixed connective tissue disease.)
    Asthma: Symptoms include wheezing or difficulty breathing when breathing.
    Respiratory depression: shortness of breath, difficulty in breathing, etc.

    3. The following symptoms may occur after taking this medicine. If these symptoms persist or worsen, discontinue use and consult a doctor or pharmacist with this leaflet.
    Dry mouth, constipation, diarrhea, drowsiness

    4. If symptoms do not improve after taking the medicine 5 to 6 times, stop taking the medicine and consult a doctor or pharmacist with this leaflet (especially if fever lasts for 3 days or more or occurs repeatedly).

  • Relief  of cold symptoms (runny nose, stuffy nose, sneezing, sore throat, cough, phlegm, chills, fever, headache, joint pain, muscle pain)

  • Take the following dose with water or hot water
    Adults (15 years of age and older)
    Dosage2 tablets
    Number of doses per dayPlease take within 30 minutes after your third meal.
    Under 15
    Dosage-
    Number of doses per dayPlease do not take.
    <Precautions related to usage and dosage>
    (1) Please strictly follow the instructions for use and dosage.
    (2) How to remove the tablets

    As shown in the diagram on the right, firmly press the raised part of the PTP sheet containing the tablet with your fingertip to break the aluminum foil on the back, remove the tablet, and take it.
    (If accidentally swallowed whole, it can lead to unexpected accidents such as the esophageal mucosa becoming lodged in it.)

    *Please use this medicine after receiving an explanation from a pharmacist and carefully reading the “Precautions for Use”. If you have allergies, please be sure to consult with us.

  • Loxoprofen sodium hydrate
    Quantity (out of 6 tablets)204.3mg (180mg as anhydrous)
    FunctionActs on prostaglandins, the source of inflammation and pain, to relieve sore throat, etc. and reduce fever.
    Dihydrocodeine phosphate
    Quantity (out of 6 tablets)24mg
    FunctionActs on the cough center to relieve cough.
    dl-methylephedrine hydrochloride
    Quantity (out of 6 tablets)60mg
    FunctionExpands bronchi and relieves coughing.
    Bromhexine hydrochloride
    Quantity (out of 6 tablets)12mg
    FunctionMakes it easier to release sputum, which is one of the causes of coughing.
    Clemastine fumarate
    Quantity (out of 6 tablets)1.34mg
    FunctionRelieves cold allergy symptoms (runny nose, stuffy nose, etc.).
    [Additives]
    D-mannitol, cellulose, hydroxypropyl cellulose, croscarmellose sodium, magnesium stearate, hypromellose, titanium oxide, talc, carnauba wax

  • (1) Store in a cool, dry place away from direct sunlight.
    (2) Please keep out of reach of children.
    (3) Please do not replace it with another container. (This may cause misuse or change in quality)
    (4) Do not use products whose expiration date has passed.

  • LOXONIN General Cold Medicine

    Packaging unit 12 tablets24 tablets
    Manufacturer's suggested retail price (10% tax included) 1,380円(1,518円)1,980円(2,178円)
    JAN Code 4987 107 6736954987 107 673701
    Individual packaging size Width x Depth x Height (mm) 123x20x80123x27x80
    Packaging unit
    12 tablets / 24 tablets
    Manufacturer's suggested retail price (10% tax included)
    12 tablets 1,380円(1,518円)
    24 tablets 1,980円(2,178円)
    JAN Code
    12 tablets 4987 107 673695
    24 tablets 4987 107 673701
    Individual package size width x depth x height (mm)
    12 tablets 123x20x80
    24 tablets 123x27x80

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