Improve melasma in 8 weeks
The only OTC drug* that show improvement on those stubborn spots and
melisma, that have been considered difficult to cure.
Use continuously for 8 weeks and see improvement of your melasma.
*As OTC drug (as of February 2021)
Spots (limited to melasma)
Take the following amount with water or hot water.
Adults (15 years old and over):
Take 2 tablets at a time twice daily after meals.
Do not use for children under 15 years old.
This tablet contains the following ingredients in 4 tablets:
Ascorbic Acid (Vitamin C)
Additives: Calcium lactate, crystalline cellulose, croscarmelose sodium, hydroxypropyl cellulose, magnesium stearate, hypromellose, macrogol, talc, titanium oxide, iron sesquioxide, and carnauba wax.
Blocks melanocyte activator
prior to melanin production
Inhibits production of
tyrosinase that forms melanin
Direct reduction of
Tranexamic acid inhibits plasmin signaling at an early stage.
L-cysteine and Vitamin C suppress the excessive formation of melanin, which is the root cause of spots.
Vitamin C directly reduces melanin. L-cysteine and Vitamin B6 normalize skin turnover and promote melanin excretion.
Rate of effectiveness of TRANSINO Ⅱ in improving pigmentation during each evaluation period(Skin Tone Color Scale Evaluation)
During evaluation periods of 2 weeks, 4 weeks, 6 weeks, or 8 weeks, TRANSINO Ⅱ's improvement rate (rate of effectiveness in improving pigmentation)* was 29.5%, 62.6%, 73.7%, and 85.2%, respectively. In addition, both prominent improvement and improvement cases were confirmed 2 weeks after the administration, and both increased over time until the end of 8 weeks.
*Improvement rate = (Number of prominent improvement cases + Number of improvement cases + Number of slight improvement cases) / Total
|Difference between before and after administration||Difference between before and after administration|
|1.0 or more||Prominent Improvement|
|less than 0.25||Worsen|
Image diagnosis (V-value) result
V-value: Lightness of the specified part* based on RSA-100 skin image analysis system.
Test: Comparison between before and after administration by Paird Sample t-test (FAS analysis)
By using RSA-100 (Robo Skin Analyzer), the lightness (V-value) of the specified part* was compared before the start of TRANSINO Ⅱ administration and at the end of administration (8 weeks after administration). As a result, the lightness has increased significantly.
*The darkest area of the melasma site marked by the physician attending at the time of first imaging.
Improvement of subjective
symptoms after administration
(8 weeks after administration)
More than 70%* of respondents answered that "Spots became less noticeable" or "Skin feels brighter now."
*Agree + Somewhat agree
INTERNAL AND EXTERNAL
Please select the spots treatment specific to your type of spots
and according to your lifestyle
INTERNAL AND EXTERNAL
Please select the spots treatment
specific to your type of spots and
according to your lifestyle