close
The only remedy for melasma. The only remedy for melasma.
The only remedy for melasma.

Improve your melasma in 8 weeks. TRANSINO WhiteC clear

CONCEPT

Improve melasma in 8 weeks

肝斑のイメージ

The only OTC drug* that show improvement on those stubborn spots and
melisma, that have been considered difficult to cure.
Use continuously for 8 weeks and see improvement of your melasma.

*As OTC drug (as of February 2021)

LINEUP

  • トランシーノ ホワイトC クリア 60錠

    60tablets for
    15-day
    supply

    TRANSINO PTP

    60 tablets

    First class OTC drug

    Start with this trial size package

    15-day supply (60 tablets)

  • トランシーノ ホワイトC クリア 120錠

    120tablets for
    30-day
    supply

    TRANSINO PTP

    120 tablets

    First class OTC drug

    Affordable 4-week package
    30-day supply (120 tablets)
    Approx. 1 month supply

  • トランシーノ ホワイトC クリア 120錠

    240tablets for
    60-day
    supply

    TRANSINO PTP

    240 tablets

    First class OTC drug

    Complete package designed to last
    for approximately 8 weeks
    60-day supply (240 tablets)
    Approx. 2-month supply

Indication

Spots (limited to melasma)

Dosage and
administration

Take the following amount with water or hot water.

Adults (15 years old and over):

Take 2 tablets at a time twice daily after meals.

Do not use for children under 15 years old.

Ingredients

This tablet contains the following ingredients in 4 tablets:

Tranexamic Acid

750mg

L-cysteine

240mg

Ascorbic Acid (Vitamin C)

300mg

Pyridoxine hydrochloride
(Vitamin B6)

6mg

Calcium Pantothenate

24mg

Additives: Calcium lactate, crystalline cellulose, croscarmelose sodium, hydroxypropyl cellulose, magnesium stearate, hypromellose, macrogol, talc, titanium oxide, iron sesquioxide, and carnauba wax.

The main component of
TRANSINO Ⅱ is tranexamic acid.

Improve melasma in 3 steps!

  • Step 1

    step1

    Tranexamic acid inhibits plasmin signaling at an early stage.

    Step 2

    step2

    L-cysteine and Vitamin C suppress the excessive formation of melanin, which is the root cause of spots.

    Step 3

    step3

    Vitamin C directly reduces melanin. L-cysteine and Vitamin B6 normalize skin turnover and promote melanin excretion.

Effect of TRANSINO Ⅱ
according to the data

By taking it twice a day for 8 weeks
(2 months), it was confirmed to be highly effective in improving "melasma."

Rate of effectiveness of TRANSINO Ⅱ in improving pigmentation during each evaluation period(Skin Tone Color Scale Evaluation)

Rate of effectiveness of TRANSINO Ⅱ in improving pigmentation during each evaluation period (Skin Tone Color Scale Evaluation) Rate of effectiveness of TRANSINO Ⅱ in improving pigmentation during each evaluation period (Skin Tone Color Scale Evaluation)

During evaluation periods of 2 weeks, 4 weeks, 6 weeks, or 8 weeks, TRANSINO Ⅱ's improvement rate (rate of effectiveness in improving pigmentation)* was 29.5%, 62.6%, 73.7%, and 85.2%, respectively. In addition, both prominent improvement and improvement cases were confirmed 2 weeks after the administration, and both increased over time until the end of 8 weeks.

*Improvement rate = (Number of prominent improvement cases + Number of improvement cases + Number of slight improvement cases) / Total

Criterial for improving pigmentation
Difference between before and after administration Difference between before and after administration
1.0 or moreProminent Improvement
0.75Improvement
0.5Slight Improvement
-0.25~0.25No Change
less than 0.25Worsen
Significant lightening of melasma was confirmed 8 weeks after administration.

TRANSINO Ⅱ
Image diagnosis (V-value) result

TRANSINO Ⅱ Image diagnosis (V-value) result TRANSINO Ⅱ Image diagnosis (V-value) result

V-value: Lightness of the specified part* based on RSA-100 skin image analysis system.
Test: Comparison between before and after administration by Paird Sample t-test (FAS analysis)

By using RSA-100 (Robo Skin Analyzer), the lightness (V-value) of the specified part* was compared before the start of TRANSINO Ⅱ administration and at the end of administration (8 weeks after administration). As a result, the lightness has increased significantly.

*The darkest area of the melasma site marked by the physician attending at the time of first imaging.

Improvement of subjective symptoms was confirmed

Improvement of subjective
symptoms after administration
(8 weeks after administration)
(FAS analysis)

Improvement of subjective symptoms after administration (8 weeks after administration) (FAS analysis) Improvement of subjective symptoms after administration (8 weeks after administration) (FAS analysis)

More than 70%* of respondents answered that "Spots became less noticeable" or "Skin feels brighter now."

*Agree + Somewhat agree

Safety

The occurrence of adverse reactions was 5.2% (6/115 cases) with a total of 8 cases reported (5 gastrointestinal disorders, 1 case of abdominal pain, 2 abnormal laboratory test values). All were mild cases and no serious cases were found. <Attached Data at the Time of Application for Approval>

INTERNAL AND EXTERNAL

Please select the spots treatment specific to your type of spots
and according to your lifestyle

  • Melasma
  • Spots
  • UV
  • Internal
  • External

INTERNAL AND EXTERNAL

Please select the spots treatment
specific to your type of spots and
according to your lifestyle

Internal
( Oral medicine )
art01

For melasma

TransinoⅡ

TRANSINO®

First class OTC drug

more
art02

For melasma

WhiteC clear

TRANSINO®
WhiteC clear

Third class OTC drug

more
External
( Medicated Skincare )
art03
TransinoⅡ

TRANSINO®
Skincare Series

Medical Cosmetic

more